Archive for the ‘Rare Diseases’ Category
They suffer from gout? Get help and find some relief
Often complain they of joint pains? Many people suffer from arthritis, and one of the most forms of arthritis. Gout is often more concentration of uric acid in the body. When there is an excess of uric acid in the body, these forms in tiny urato crystals that usually forms in body tissues especially around common areas. When these crystals forming around the inflammation of the joints to establish, the patient experiences pain. Once the droplet becomes chronic, a hard deposit of uric acid in joint tissues can be seen that it can lead to joint destruction. In addition, chronic gout can also lead to a decrease in the kidney’s ability to function normally.
An attack of gout usually follows injury. It can also result from the ingestion of diuretic often used to treat hypertension. The pain that accompanies a gout attack usually lasts up to two weeks. Untreated gout can put a person at risk of developing kidney stones, and arthritis in the feet or knees. It is estimated that some 5 million people in the United States suffer from gout. The disease is most commonly seen in men than in women.
The causes of gout are varied. The inheritance is sometimes a factor in the development of gout. Those who have inherited an abnormal processing of uric acid in the body most likely will develop gout. Other factors that contribute to the development of gout are high blood pressure, obesity, and alcohol abuse.
If you suffer from gout can find ways to treat pain and discomfort that comes with the disease. Diet and low alcohol are some of the ways of controlling the development of gout. Prevention of uric acid is considered that you among the best measures in the treatment of gout.
Preventing the production of uric acid can be made through prescription. This can also be done through avoid purine-rich foods. Purines are compounds that contain uric acid. Some of the food that is needed to avoid because they contain uric acid include organ meats such as liver and kidney, Sweetbreads, anchovies and sardines. Avoid these food items can help reduce the incidence of gout attack. The consumption of fructose that is normally found in soft drinks also shows an increase in the risk of gout. Finally, reducing its weight also will help limit the risk of attacks of gout.
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Peritoneal mesothelioma
Malignant peritoneal mesothelioma is a rare form of cancer that develops in the thin cell walls that surround the abdominal cavity, called the peritoneum. Other types of cancer, including mesothelioma malignant pleural mesothelioma, which occurs in the cell wall that surrounds the lungs and malignant pericardial mesothelioma, which occurs in the pericardial wall of the house. peritoneal mesothelioma is the rarest form, the second of the disease and accounts for approximately 20% of cases of mesothelioma each year.
What causes peritoneal mesothelioma?
Peritoneal mesothelioma is known to be caused by exposure to asbestos. Asbestos is said to reach the abdominal wall by one of two methods. The first is through the ingestion of asbestos fibers that are processed by digestion and stay in the peritoneum. The other method is through the lungs and lymph nodes by inhaled asbestos fibers. Malignant pleural mesothelioma is also known to metastasize directly into the abdominal cavity, if disclosure is not slower.
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FDA Approves New Drug for Pompe Disease
The Food and Drug Administration has approved a new drug for people with late-onset Pompe disease. This is called alpha alglucosidase (Lumizyme).
Pompe disease affects between 5,000 and 10,000 people worldwide. It is a rare lysosomal storage disorder caused by lack of an enzyme called acid alpha-1 ,4-glucosidase. This lack leads to an accumulation of glycogen, eventually leading to muscle damage, and can be fatal when respiratory and cardiovascular systems are affected.
Lumizyme replaces alpha-glucosidase is required (GAA) in the body, thus reducing the accumulation of glycogen. The drug, which was approved on the basis of a study of 90 patients between 10 and 70 years, has not been approved for younger patients suffering from Pompe disease. The other effective drug Myozyme market – which has been approved for patients younger people – are currently in short supply and is reserved for those with Pompe disease, less than 8 years.
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